THE HYPOXIA-DRIVEN CROSSTALK BETWEEN TUMOR AND TUMOR-ASSOCIATED MACROPHAGES: MECHANISMS AND CLINICAL TREATMENT STRATEGIES

The hypoxia-driven crosstalk between tumor and tumor-associated macrophages: mechanisms and clinical treatment strategies

Abstract Given that hypoxia is a persistent physiological feature of many different solid tumors and a key driver for cancer malignancy, it is thought to be a major target in cancer treatment recently.Tumor-associated macrophages (TAMs) are the most abundant immune cells in the tumor microenvironment (TME), which have a large impact Bath Light on t

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Clinically amyopathic dermatomyositis presenting with isolated facial edema complicated by acute respiratory failure: a case report

Abstract Background In clinically amyopathic dermatomyositis, the hallmark cutaneous manifestations are the key to diagnosis.We report a case of clinically amyopathic dermatomyositis which presented with facial edema as the sole cutaneous manifestation and was later complicated by acute respiratory failure leading to death.Case presentation A 58-ye

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Religion and Alexander the Great

Alexander the Great was religiously both a man of his time and the catalyst for change in the pattern of Greek religious life.He accepted the ubiquity of divine presence in the world and Skincare, Beauty and Hygiene Products participated actively in the practice of Greek paganism, Card but he was also imbued with his own importance which evolved ov

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